№ 59-4 (том 1): ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, Февраль, 2025
Научно-образовательные статьи

CITRIC ACID PRODUCTION WITH ASPERGILLUS NIGER

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  • Amannepesova Humay,
  • Yazmyradova Gurbanjemal,
  • Nargiza Ismayilova
Amannepesova Humay
Oguzhan Engineering and Technology University of Turkmenistan. Ashgabat, Turkmenistan
Yazmyradova Gurbanjemal
Oguzhan Engineering and Technology University of Turkmenistan. Ashgabat, Turkmenistan
Nargiza Ismayilova
Oguzhan Engineering and Technology University of Turkmenistan. Ashgabat, Turkmenistan

Опубликован 25.03.2025

Ключевые слова

  • Citric acid,
  • Aspergillus niger,
  • fermentation,
  • biotechnology,
  • metabolic engineering,
  • industrial microbiology,
  • bioprocess optimization
    • ...Больше
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Как цитировать

H. Amannepesova, G. Yazmyradova, & N. Ismayilova. (2025). CITRIC ACID PRODUCTION WITH ASPERGILLUS NIGER. ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, 59-4 (том 1). https://mpcareer-google.ru/index.php/journal/article/view/1186

Аннотация

Citric acid is a widely used organic acid with applications in food, pharmaceuticals, and industrial biotechnology. The most common method for its commercial production is fermentation using Aspergillus niger, a filamentous fungus with high citric acid yield. This paper discusses the biochemical mechanisms, fermentation conditions, process optimization, and industrial-scale production of citric acid with A. niger. Key factors such as carbon sources, pH, aeration, and metal ion concentrations significantly affect production efficiency. Advances in metabolic engineering and bioprocess innovations have further enhanced citric acid yields, making microbial fermentation the dominant production method.

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Библиографические ссылки

  1. Papagianni, M. (2007). Advances in citric acid fermentation by Aspergillus niger: Biochemical aspects, process optimization, and strain improvement. Biotechnology Advances.
  2. Show, P. L., et al. (2015). Sustainable citric acid production from agro-industrial waste using filamentous fungi. Journal of Industrial Microbiology & Biotechnology.
  3. Karaffa, L., & Kubicek, C. P. (2019). The key role of glucose transport in citric acid production by Aspergillus niger. Applied Microbiology and Biotechnology.