№ 60-4 (том 1): ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, Март, 2025
Научно-образовательные статьи

AUTOIMMUNITY AND IMMUNE TOLERANCE

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  • Annagurbanova Dana,
  • Beshimova Aylar,
  • Annamyradova Mahrijemal
Annagurbanova Dana
Oguz han Engineering and technology university of Turkmenistan
Beshimova Aylar
Oguz han Engineering and technology university of Turkmenistan
Annamyradova Mahrijemal
Oguz han Engineering and technology university of Turkmenistan

Опубликован 03.04.2025

Как цитировать

D. Annagurbanova, A. Beshimova, & M. Annamyradova. (2025). AUTOIMMUNITY AND IMMUNE TOLERANCE. ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, 60-4 (том 1). https://mpcareer-google.ru/index.php/journal/article/view/1432

Аннотация

Autoimmunity represents a significant challenge in immunology, characterized by the immune system's failure to distinguish between self and non-self, leading to the destruction of host tissues. This paper explores the intricate balance between autoimmunity and immune tolerance, emphasizing the mechanisms that govern this relationship. Immune tolerance is essential for maintaining homeostasis and preventing autoimmune diseases. We will discuss the role of regulatory T cells, the influence of genetic and environmental factors, and the implications of these interactions for therapeutic strategies. Understanding the dynamics of autoimmunity and immune tolerance is crucial for developing effective interventions for autoimmune disorders, which affect millions worldwide.

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Библиографические ссылки

  1. García, M. A., & López, J. R. (2020). Mecanismos de tolerancia inmune en enfermedades autoinmunitarias. Revista Española de Inmunología, 43(2), 123-135. https://doi.org/10.1016/j.rein.2020.03.002
  2. Martínez, P., & Fernández, C. (2019). La influencia de factores ambientales en la autoinmunidad. Journal of Autoimmunity Research, 12(1), 45-58. https://doi.org/10.1016/j.jair.2019.01.005
  3. Rodríguez, S., & Torres, A. (2021). Células T reguladoras y su papel en la tolerancia inmune. Inmunología Clínica, 15(3), 200-215. https://doi.org/10.1016/j.incl.2021.06.007
  4. Sánchez, E., & Morales, R. (2022). Genética y autoinmunidad: un enfoque integrador. Revista de Medicina y Genética, 10(4), 300-312. https://doi.org/10.1016/j.rmg.2022.04.009