№ 75-1 (том 1): ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, Июнь, 2026
Научно-образовательные статьи

HISTOMORPHOLOGICAL CHANGES IN THE RETINA OF RATS EXPOSED TO CHRONIC IMMOBILIZATION STRESS

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  • Rajabov Bekzod Madirim o'g'li
Rajabov Bekzod Madirim o'g'li
Tashkent State Medical University

Опубликован 16.06.2026

Ключевые слова

  • chronic stress, retina, immobilization stress, histology, neurodegeneration, rat model.

Как цитировать

B. M. Rajabov. (2026). HISTOMORPHOLOGICAL CHANGES IN THE RETINA OF RATS EXPOSED TO CHRONIC IMMOBILIZATION STRESS. ОБРАЗОВАНИЕ И НАУКА В XXI ВЕКЕ, 75-1 (том 1). https://mpcareer-google.ru/index.php/journal/article/view/5797

Аннотация

Chronic stress is recognized as one of the major factors affecting the structural and functional integrity of various organs and tissues. The visual system, particularly the retina, is highly sensitive to metabolic and vascular disturbances induced by prolonged stress exposure. The present study aimed to evaluate histomorphological changes in the retina of rats subjected to chronic immobilization stress. Twenty adult male Wistar rats were divided into control and experimental groups. Animals in the experimental group were exposed to immobilization stress for 2 hours daily over a period of 21 days. Retinal tissue samples were collected and processed for histological examination using hematoxylin and eosin staining. Microscopic analysis revealed structural alterations in retinal layers, including thinning of the ganglion cell layer, reduced cellular density, and vascular congestion. Degenerative changes were more pronounced in the inner retinal layers compared to controls. These findings suggest that chronic immobilization stress may induce significant retinal damage and contribute to neurodegenerative processes within the visual system.

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